In vitroDNA-based Predator–Prey System with Oscillatory Kinetics

Ackermann, J., B. Wlotzka, and J. S. McCaskill. “In vitroDNA-based Predator–Prey System with Oscillatory Kinetics.” Bulletin of Mathematical Biology 60, no. 2 (1998): 329-354.
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A coupled system of two isothermalin vitro DNA/RNA amplification reactions using different primers is modeled kinetically with realistic rate parameters and shown to exhibit oscillatory behavior in a flow reactor. One of the two isothermal amplification reactions acts as a predator of the other, the prey. The mechanism of the oscillatory behavior is analyzed in terms of a hierarchy of kinetic models. The work provides an insight into the choice of parameters for experiments. The latter are important in providing detailed insight into the complex processes of ecological interactions and their evolution.

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